Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved. No more bleeding issues.

FDA approves dabigatran for stroke prevention, embolism, in AF patients

 

The US FDA has approved dabigatran (Pradaxa) for the prevention of stroke and systemic embolism in patients with atrial fibrillation. The drug will be available in two doses: 150 mg twice daily and, for a small subset with severe renal impairment, 75 mg twice daily. At last there is an oral anticoagulant that is at least as safe and effective as warfarin but is more consistent in its effects and does not require cumbersome anticoagulation monitoring or careful attention to diet.

Health-Atrial Fibrillation medications-Dabigatran VS Coumadin – New England Journal of Medicine says that Dabigatan is BETTER

 

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27 Responses to Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved. No more bleeding issues.

  1. […] Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved. No more bleeding issues. &la… […]

  2. Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved ……

    Here at World Spinner we are debating the same thing……

  3. gail adinolfi says:

    Can predaxa be reversed readily in case of surgery?

  4. txlady706 says:

    gail adinolfi:
    I’m not sure, but I’m not sure that you would need to, since the reason that this is a big breakthrough IS that it doesn’t have the BLEEDING issues. Please, consult a doctor, though. I try to keep up with issues, because I have a mom that uses it. I am not medically licensed in anyway. I’m a computer hardware engineer by profession. Take care and g-d bless you.

  5. jo says:

    Life for my sister has been very stressful since they put her on Coumadin. She has gotten so bad that she is even afraid to go out because she might have an accident and bleed to death. Is there an alternative?

    • David Hewitt says:

      She needs thrombelastography to determine (1) IF she needs treatment and (2) WHICH treatment and (3) HOW MUCH treatment.

  6. txlady706 says:

    My mother was very scared at first, but she’s dealing with it. It’s an adjustment. I’m trying to see if one of her doctors would put her on dabigatran (Pradaxa), but I’m afraid that it’s not covered yet in the insurance and I’m not rich. I’m really pinching pennies as it is. I could not afford it, if it’s not covered unless it’s like $20 a month, but most meds are supper expensive — like $200-$300 and some $500-$600. I would not be able to pay the mortgage or food.

  7. Fiona B. says:

    It was also discovered to work for those over 75 years old with atrial fibrillation who want to prevent strokes. Yet ITS NOT APPROVED in the US!

    http://www.theheart.org/article/1233275.do

    • txlady706 says:

      It’s available now -under the name PRADAXA
      Good luck

    • jen says:

      Believe me, you can get it in the United States!! My mom was put on Pradaxa for minor AFib. Otherwise, she was in excellent health. She died within two weeks of starting the Pradaxa. She was 76 and her cardiologist had told her she had the heart of a 20 yr old except for the MINOR AFib. She bled to death in the MICU. Pradaxa killed her!!

      • txlady706 says:

        jen:
        I’m sorry for your loss

      • SLSW says:

        I feel your loss, my brother in law also lost his life to Pradaxa, no reversal, I wish they would take it off the market!

        • anonymous says:

          My mother bleed to death 4 days ago thanks to Pradaxa. Learned a lot in the past 8 days. Drs. do not know enough about the drug to be dispensing it like they do. Emergency room Drs and nurses are livid about the use of this drug because they are left to handle and communicate the difficulty of reversing the effects of the drug. THERE ARE NO REVERSAL AGENTS AVAILABLE FOR PRADAXA. With proper kidney functions it should reverse itself within 24 hours. Kidney function is what regulates this drug (no test currently available to ck if there is to much in your system). If your kidneys are impaired or fail due to any other ailment (such as UTI, kidney stone etc.) it cannot process the drug effectively. If not processed effectively it builds up and you begin to bleed. Dialysis could help but if your blood is to thin because of the pradaxa it is very risky for Dr to put in a port for the dialysis. If on it or planning to get on it ASK QUESTIONS. PROPER KIDNEY FUNCTION IS CRITICAL TO AVOID MAJOR ISSUES WITH THIS DRUG. TAKE KIDNEY STONES, UNRINARY TRACK INFECTIONS (UTI) OR ANY OTHER KIDNEY AILMENTS SERIOUSLY WHEN ON THIS DRUG. PARTICULARLY IN OLDER PATIENTS. I may not know enough yet but would BEG all of you to ask the questions and find out if your kidneys are strong enough for the drug. If you do not get straight answers find another Dr that knows more about the drug and its effects. Mildly impaired kidneys could be a major issue when using this drug.

      • Anonymous says:

        I’m so sorry to hear of your loss. My 85 yr Mom was put on Predaxa for afib 2 weeks ago. Within a week she had fallen 3 times. She was weak, tired, mentally foggy, anal bleeding, stomach bloated, joints hurt. I didn’t catch on at first because she has chronic UTIs and I thought the symptoms were from that as she has had falls before when having UTI. Could have been partly that but she only had a mild one. The third fall led us to hospital with a 9cm gash in her arm and 18 stitches. It is still bleeding a bit 4 days later even with stitches. I stopped Predaxa day after the fall (had thought of stopping it day before as I was worried about bleeding with all the falls and talked to doc. wish i had stopped it that day). Todayshe is much more alert and starting to seem more herself again. I hope we stopped it in time to prevent the internal bleeding that your Mom experienced. I don’t think there is enough info out there for people or docs on this drug.

      • anonymous says:

        it is certainly available. My mother bleed to death 4 days ago thanks to Pradaxa. Learned a lot in the past 8 days. Drs. do not know enough about the drug to be dispensing it like they do. Emergency room Drs and nurses are livid about the use of this drug because they are left to handle and communicate the difficulty of reversing the effects of the drug. THERE ARE NO REVERSAL AGENTS AVAILABLE FOR PRADAXA. With proper kidney functions it should reverse itself within 24 hours. Kidney function is what regulates this drug (no test currently available to ck if there is to much in your system). If your kidneys are impaired or fail due to any other ailment (such as UTI, kidney stone etc.) it cannot process the drug effectively. If not processed effectively it builds up and you begin to bleed. Dialysis could help but if your blood is to thin because of the pradaxa it is very risky for Dr to put in a port for the dialysis. If on it or planning to get on it ASK QUESTIONS. PROPER KIDNEY FUNCTION IS CRITICAL TO AVOID MAJOR ISSUES WITH THIS DRUG. TAKE KIDNEY STONES, UNRINARY TRACK INFECTIONS (UTI) OR ANY OTHER KIDNEY AILMENTS SERIOUSLY WHEN ON THIS DRUG. PARTICULARLY IN OLDER PATIENTS. I may not know enough yet but would BEG all of you to ask the questions and find out if your kidneys are strong enough for the drug. If you do not get straight answers find another Dr that knows more about the drug and its effects. Mildly impaired kidneys could be a major issue when using this drug.

        • Anonymous says:

          my brother had a stent put in after a heart attack and put on pradaxa 19 days later he bled to death from a brain hemorrage. We buried him yesterday, he was 76 years old. The pain of losing such a healthy, strong and loving human being is so extremely sad and painfully difficult. This drug should not be allowed on the market period.

  8. Anonymous says:

    I am a graduate nurse. Warfarin has an antagonist. Is the same true for Pradaxa?

    • txlady706 says:

      I don’t know. I’m not a doctor.

    • SLSW says:

      Pradaxa works in a different way than coumadin, as of right now no counteraction against it, once you start bleeding that is it!

    • David Hewitt says:

      As a pathologist and director of a hospital clinical laboratory, I must suggest that everyone who is considered for Pradaxa–or ANY anticoagulant or antiplatelet therapy–be evaluated FIRST with thrombelastography. This test will determine exactly WHICH therapy is indicated, and to what degree the therapy is effective. SO MANY people end up with the wrong therapy. Pradaxa is particularly scray in patients with compromised renal function–like MOST older people.

  9. Anonymous says:

    Correct once you start bleeding only dialysis will help you or blood transfusions. As stated you are done if you bleed on Pradaxa. I would stick with coumadin which can easily be controlled.Only an idiot would use a drug that can cause hemmorage with no antidote. Not me I stay with coumadin.

  10. bv cures says:

    bv cures…

    […]Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved. No more bleeding issues. « Politics, Religion, and Family[…]…

  11. maskeen singh…

    […]Coumadin / Warfarin users – Dabigatran (Pradaxa) is FDA approved. No more bleeding issues. « Politics, Religion, and Family[…]…

  12. Madeline Wolly says:

    I’m 88 years old and trying to decide whether to take prodaxa, xeralto or warfarin. lab work shows. kidney function is normal. What is thrombolastography ?

  13. Anonymous says:

    where can I find pradaxa 150 mg ?

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